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KMID : 0882420130850050503
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Korean Journal of Medicine
2013 Volume.85 No. 5 p.503 ~ p.506
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A Case of Drug-Induced Autoimmune Hepatitis after Glucosamine Ingestion
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Kwon Seong-Soon
Wee Jee-Wan
Park Jung-Wan
Yoon Seug-Yun
Jeong Soung-Won
Jang Jae-Young
Jin Yoon-Mi
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Abstract
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Herbal remedies and health foods are widely used, and their side effects have been reported. Glucosamine is a naturally occurring amino-monosaccharide and a safe health food; rarely, however, it can cause cholestatic and hepatocellular hepatitis. We describe a case of drug-induced autoimmune hepatitis after ingestion of glucosamine. A middle-aged woman who had no history of liver disease complained of jaundice after taking glucosamine. The diagnosis of drug-induced acute autoimmune hepatitis was made using the Roussel Uclaf Causality Assessment Method score based on the patient’s history and laboratory data, and percutaneous liver biopsy. After supportive care and administering prednisolone and azathiprine, the patient showed rapid improvement in clinical symptoms and laboratory findings.
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KEYWORD
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Glucosamine, Toxic hepatitis, Autoimmune hepatitis, Drug induced autoimmune hepatitis
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